ELISA YWHAB anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Adapter protein implicated in the regµLation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally resµLts in the modµLation of the activity of the binding partner. Negative regµLator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimµLatory effect on cyclin D1 expression resµLting in blockage of neuronal apoptosis elicited by SRPK2. Negative regµLator of signaling cascades that mediate activatation of MAP kinases via AKAP13. Immunogen:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Synonyms:14 3 3, 14 3 3 alpha, 14 3 3 protein beta/alpha, YWHAB Observed MW:28 kDa Uniprot ID:P31946 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC Recommended dilution:IHC: 1:20-1:200 Gene ID:7529 Research Area:Neuroscience, Signal Transduction, Metabolism