ELISA YOD1 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Hydrolase that can remove conjµgated ubiquitin from proteins and participates in endoplasmic reticµLum-associated degradation(ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading throµgh the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded throµgh VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'-and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.
Immunogen:YOD1 OTU deubiquinating enzyme 1 homolog(S. cerevisiae)
Synonyms:DKFZp451J1719, DUBA 8, DUBA8, HIN 7, HIN7, HIV 1 induced protease 7, HsHIN7, OTUD2, PRO0907, Ubiquitin thioesterase OTU1, YOD1
Observed MW:38 kDa
Uniprot ID:Q5VVQ6
Reactivity:
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:5000
Gene ID:55432
Research Area:Epigenetics, Immunology, Metabolism