ELISA XRN1 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).
Immunogen:5'-3' exoribonuclease 1
Synonyms:5 3 exoribonuclease 1, 5' 3' exoribonuclease 1, DKFZp434P0721, DKFZp686B22225, DKFZp686F19113, FLJ41903, SEP1, XRN1
Observed MW:192 kDa
Uniprot ID:Q8IZH2
Reactivity:, Mouse
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID:54464
Research Area:Metabolism