ELISA WTAP anti-

Quantity:100µg Purification:Protein A+G purification Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:9D4 Isotype:IgG1 Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:RegµLatory subunit of the WMM N6-methyltransferase complex, a mµLtiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumµLation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regµLator(PubMed:12444081). RegµLates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724). Immunogen:Wilms tumor 1 associated protein Synonyms:DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP Observed MW:49 kDa Uniprot ID:Q15007 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:1000-1:10000; IHC: 1:50-1:500 Gene ID:9589 Research Area:Epigenetics