ELISA WT1 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Transcription factor that plays an important role in cellµLar development and cell survival. RegµLates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Immunogen:Wilms tumor 1
Synonyms:GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT 2, WT1, WT33
Observed MW:52 kDa
Uniprot ID:P19544
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC, IF, IP
Recommended dilution:WB: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200; IP: 1:500-1:5000
Gene ID:7490
Research Area:Metabolism, Immunology, Cancer, Developmental biology, Stem Cells