ELISA WRAP53 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regµLation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage. Immunogen:WD repeat containing, antisense to TP53 Synonyms:FLJ10385, TCAB1, WDR79, WRAP53 Observed MW:72 kDa Uniprot ID:Q9BUR4 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:1000 Gene ID:55135 Research Area:Metabolism