ELISA WEE2 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regµLator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).
Immunogen:WEE1 homolog 2(S. pombe)
Synonyms:FLJ16107, WEE1 homolog 2(S. pombe), Wee1 like protein kinase 1B, Wee1 like protein kinase 2, WEE1B, Wee1B kinase, WEE2
Observed MW:63 kDa
Uniprot ID:P0C1S8
Reactivity:
Tested Application:ELISA, WB
Recommended dilution:WB: 1:200-1:2000
Gene ID:494551
Research Area:Developmental biology, Signal Transduction