ELISA WDR24 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regµLated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regµLation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823). Immunogen:WD repeat domain 24 Synonyms:C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24 Observed MW:102 kDa Uniprot ID:Q96S15 Reactivity:, Mouse Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200 Gene ID:84219 Research Area:Cell Division and Proliferation