ELISA WDFY3 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Required for selective autophagy(aggrephagy) but not for autophagic degradation of bµLk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies(p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies sµggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation. Immunogen:WD repeat and FYVE domain containing 3 Synonyms:ALFY, Autophagy linked FYVE protein, KIAA0993, WDFY3, ZFYVE25 Observed MW: Uniprot ID:Q8IZQ1 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC Recommended dilution:IHC: 1:20-1:200 Gene ID:23001 Research Area:CardiovascµLar, Signal Transduction