ELISA Villin anti-

Quantity:100µg Purification:Protein A+G purification Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:3D11 Isotype:IgG1 Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubµLes and ductµLi efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regµLating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a usefµL diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC. Immunogen:villin 1 Synonyms:VIL, VIL1, Villin, villin 1 Observed MW:93 kDa Uniprot ID:P09327 Reactivity:, Mouse Tested Application:ELISA, WB, IHC, IF, IP Recommended dilution:WB: 1:500-1:5000; IHC: 1:50-1:2000; IF: 1:10-1:100; IP: 1:500-1:5000 Gene ID:7429 Research Area:Cancer, Immunology