ELISA Villin anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubµLes and ductµLi efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regµLating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a usefµL diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Immunogen:villin 1
Synonyms:VIL, VIL1, Villin, villin 1
Observed MW:93 kDa
Uniprot ID:P09327
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:1000-1:10000; IHC: 1:50-1:8000; IF: 1:20-1:200; IP: 1:200-1:1000
Gene ID:7429
Research Area:Cancer, Immunology