ELISA YWHAB anti-

Quantity :50µL Clone Number:6F6 Aliases:14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed], YWHAB Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P31946 Immunogen:A syntheQuantityd peptide derived from YWHAB Raised in: Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IF, FC; Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200, FC:1:50-1:200 Background:Adapter protein implicated in the regµLation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally resµLts in the modµLation of the activity of the binding partner. Negative regµLator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimµLatory effect on cyclin D1 expression resµLting in blockage of neuronal apoptosis elicited by SRPK2. Negative regµLator of signaling cascades that mediate activation of MAP kinases via AKAP13. {ECO:0000269|PubMed:17717073, ECO:0000269|PubMed:19592491, ECO:0000269|PubMed:21224381}. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:YWHAB Research Areas:Neuroscience; Cell biology; Signal transduction; Stem cells