ELISA XRCC4 anti-

Quantity :100µL Clone Number: Aliases:DNA double strand break repair and V(D)J recombination protein XRCC4 antibody; DNA repair protein XRCC4 antibody; SSMED antibody; X ray repair complementing defective repair in Chinese hamster cells 4 antibody; X ray repair cross complementing 4 antibody; X ray repair cross complementing protein 4 antibody; X-ray repair cross-complementing protein 4 antibody; XRCC 4 antibody; XRCC4 antibody; XRCC4_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13426 Immunogen:SyntheQuantityd peptide derived from Internal of XRCC4. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. Ling Chen, J. Biol. Chem., Aµg 2000; 275: 26196. J Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:XRCC4 Research Areas:Epigenetics and Nuclear Signaling