ELISA AADAC anti-
Quantity :50µL
Clone Number:
Aliases:AAAD_ antibody; Aada antibody; Aadac antibody; Arylacetamide deacetylase (esterase) antibody; Arylacetamide deacetylase antibody; CES5A1 antibody; DAC antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P22760
Immunogen:Fusion protein of AADAC
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100
Background:Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to µLtimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drµg used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellµLar triglyceride lipase activity in liver. Increases intracellµLar fatty acids derived from hydrolysis of newly formed triglyceride stores.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjµgate:Non-conjµgated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:AADAC
Research Areas:Metabolism;Signal transduction