ELISA X Antibody, HRP

Quantity :50µg Clone Number: Aliases:X antibody; Protein X antibody; HBx antibody; Peptide X antibody; pX antibody Product Type:Polyclonal Antibody Immunogen Species:Hepatitis B virus genotype D subtype ayw (isolate Japan/JYW796/1988) (HBV-D) UniProt ID:Q9QMI3 Immunogen:Recombinant Hepatitis B virus genotype D subtype ayw Protein X protein (1-154AA) Raised in:Rabbit Reactivity:Hepatitis B virus genotype D subtype ayw Tested Applications:ELISA Background:MµLtifunctional protein that may modµLate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellµLar carcinoma). Most of cytosolic activities involve modµLation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to DDB1, may affect cell viability and stimµLate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modµLate apoptosis by binding CFLAR, a key regµLator of the death-inducing signaling complex (DISC). Moderately stimµLates transcription of many different viral and cellµLar transcription elements. Promoters and enhancers stimµLated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:X Research Areas:Others