ELISA WDR77 anti-
Quantity :50µg
Clone Number:
Aliases:2610312E17Rik antibody; Androgen receptor cofactor p44 antibody; C79984 antibody; HKMT1069 antibody; MEP 50 antibody; MEP-50 antibody; MEP50 antibody; MEP50_ antibody; Methylosome protein 50 antibody; MGC2722 antibody; Nbla10071 antibody; p44 antibody; p44/Mep50 antibody; RGD1310479 antibody; RP11 552M11.3 antibody; WD repeat containing protein 77 antibody; WD repeat domain 77 antibody; WD repeat-containing protein 77 antibody; WDR77 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9BQA1
Immunogen:Recombinant Methylosome protein 50 protein (1-312AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regµLation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:WDR77
Research Areas:Epigenetics and Nuclear Signaling; Signal transduction