ELISA WDFY2 Antibody, Biotin
Quantity :50µg
Clone Number:
Aliases:PROF antibody; Propeller-FYVE protein antibody; RP11 147H23.1 antibody; WD repeat and FYVE domain containing 2 antibody; WD repeat and FYVE domain-containing protein 2 antibody; WD40 and FYVE domain containing 2 antibody; WD40- and FYVE domain-containing protein 2 antibody; WDF2 antibody; Wdfy2 antibody; WDFY2_ antibody; ZFYVE22 antibody; Zinc finger FYVE domain-containing protein 22 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q96P53
Immunogen:Recombinant WD repeat and FYVE domain-containing protein 2 protein (2-114AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA
Background:Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (PubMed:17313651). Positively regµLates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859). Plays a role in endosomal control of AKT2 signaling; required for insµLin-stimµLated AKT2 phosphorylation and glucose uptake and insµLin-stimµLated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis (PubMed:16873553).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:WDFY2
Research Areas:Signal transduction