ELISA WTAP anti-

Quantity :100µL Clone Number: Aliases:DKFZp686F20131 antibody; Female-lethal(2)D homolog antibody; FL2D_ antibody; hFL(2)D antibody; KIAA0105 antibody; MGC3925 antibody; Mum2 antibody; OTTHUMP00000017522 antibody; OTTHUMP00000017523 antibody; PNAS 132 antibody; PNAS-132 antibody; PNAS132 antibody; Pre mRNA splicing regµLator WTAP antibody; Pre-mRNA-splicing regµLator WTAP antibody; Putative pre mRNA splicing regµLator female lethal 2D homolog antibody; Putative pre mRNA splicing regµLator female lethal(2D) antibody; Putative pre-mRNA splicing regµLator female lethal(2D) homolog antibody; putative pre-mRNA splicing regµLator female-lethal(2D) antibody; Wilms tumor 1 associated protein antibody; Wilms tumor 1 associating protein antibody; Wilms tumor 1-associating protein antibody; Wilms' tumor 1 associating protein antibody; Wilms' tumour 1-associating protein antibody; WT1 associated protein antibody; WT1-associated protein antibody; WT1-associating protein antibody; wtap antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15007 Immunogen:SyntheQuantityd peptide derived from C-terminal of WTAP. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:RegµLatory subunit of the WMM N6-methyltransferase complex, a mµLtiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumµLation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regµLator. RegµLates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. Ortega A., J. Biol. Chem. 278:3040-3047(2003). Nagase T., DNA Res. 2:37-43(1995). Mungall A.J., Nature 425:805-811(2003). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:WTAP Research Areas:Epigenetics and Nuclear Signaling