ELISA YOD1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:DUBA-8 antibody; DUBA8 antibody; HIN-7 antibody; HIV-1-induced protease 7 antibody; HsHIN7 antibody; OTU domain containing 2 antibody; OTU domain-containing protein 2 antibody; OTU1_ antibody; OTUD2 antibody; PRO0907 antibody; RP11-164O23.1 antibody; Ubiquitin thioesterase OTU1 antibody; yod1 antibody; YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) antibody; YOD1 OTU deubiquinating enzyme 1 homolog (yeast) antibody; YOD1 OTU deubiquinating enzyme 1; S. cerevisiae; homolog of antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q5VVQ6 Immunogen:Recombinant Ubiquitin thioesterase OTU1 protein (1-44AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Hydrolase that can remove conjµgated ubiquitin from proteins and participates in endoplasmic reticµLum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading throµgh the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded throµgh VCP\'s axial channel. Mediates deubiquitination of \'Lys-27\'-, \'Lys-29\'- and \'Lys-33\'-linked polyubiquitin chains. Also able to hydrolyze \'Lys-11\'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:YOD1 Research Areas:Cell biology; Metabolism; Signal transduction