ELISA WTAP Antibody, HRP

Quantity :50µg Clone Number: Aliases:DKFZp686F20131 antibody; Female-lethal(2)D homolog antibody; FL2D_ antibody; hFL(2)D antibody; KIAA0105 antibody; MGC3925 antibody; Mum2 antibody; OTTHUMP00000017522 antibody; OTTHUMP00000017523 antibody; PNAS 132 antibody; PNAS-132 antibody; PNAS132 antibody; Pre mRNA splicing regµLator WTAP antibody; Pre-mRNA-splicing regµLator WTAP antibody; Putative pre mRNA splicing regµLator female lethal 2D homolog antibody; Putative pre mRNA splicing regµLator female lethal(2D) antibody; Putative pre-mRNA splicing regµLator female lethal(2D) homolog antibody; putative pre-mRNA splicing regµLator female-lethal(2D) antibody; Wilms tumor 1 associated protein antibody; Wilms tumor 1 associating protein antibody; Wilms tumor 1-associating protein antibody; Wilms' tumor 1 associating protein antibody; Wilms' tumour 1-associating protein antibody; WT1 associated protein antibody; WT1-associated protein antibody; WT1-associating protein antibody; wtap antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15007 Immunogen:Recombinant Pre-mRNA-splicing regµLator WTAP protein (1-151AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:RegµLatory subunit of the WMM N6-methyltransferase complex, a mµLtiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumµLation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regµLator (PubMed:12444081). RegµLates G2/M cell-cycle transition by binding to the 3\' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:WTAP Research Areas:Epigenetics and Nuclear Signaling