ELISA WT1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:WIT 2 antibody; WT 1 antibody; AWT1 antibody; FWT1 antibody; GUD antibody; NPHS4 antibody; WAGR antibody; Wilms tumor 1 antibody; Wilms Tumor antibody; Wilms tumor protein antibody; Wilms' tumor gene antibody; Wilms' tumor protein antibody; WIT2 antibody; WT antibody; WT1 antibody; WT1_ antibody; WT33 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P19544 Immunogen:Recombinant Wilms tumor protein (1-449AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcription factor that plays an important role in cellµLar development and cell survival. RegµLates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5\'-CGCCCCCGC-3\'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:WT1 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Developmental biology; Tags & Cell Markers