ELISA WNT5A anti-

Quantity :100µL Clone Number: Aliases:hWNT 5A antibody; hWNT5A antibody; Protein Wnt 5a antibody; Protein Wnt-5a antibody; Protein Wnt5a antibody; Wingless type MMTV integration site family member 5A antibody; Wnt 5a antibody; WNT 5A protein antibody; WNT 5A protein precursor antibody; WNT5A antibody; WNT5A protein precursor antibody; WNT5A_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P41221 Immunogen: Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:2000, IHC:1:50-1:200 Background:The Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the genome that encode functionally distinct Wnt proteins. Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways. The canonical Wnt/?-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family. Aberrant activation of Wnt signaling pathways is involved in several types of cancers. Wnt-5a has been shown to signal throµgh the canonical Wnt pathways as well as throµgh non-canonical pathways and is up-regµLated in various types of cancers. In melanoma, Wnt5a is thoµght to directly affect cell motility and metastasis. Clonality:Polyclonal Isotype:IgG Purification Method:Affinity purification Conjµgate:Non-conjµgated Buffer:Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:WNT5A Research Areas:Neuroscience?Cancer;Signal transduction?Stem cells